Annals of Tropical Pathology

CASE REPORT
Year
: 2019  |  Volume : 10  |  Issue : 1  |  Page : 77--80

Epithelioid haemengioendothelioma: A report of two cases


Friday Titus Nyaku1, Theophilus Maksha Dabkana1, Haruna A Nggada2, Joasaih Miner Njem3, Stanley Tella Bwala1, Yakubu Mohammed Gana1 
1 Department of Orthopaedics and Trauma Surgery, University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria
2 Department of Human Pathology, University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria
3 Department of Surgery, University of Jos, Plateau, Nigeria

Correspondence Address:
Dr. Friday Titus Nyaku
Department of Orthopaedic Surgery, University of Maiduguri Teaching Hospital, Maiduguri, Borno State
Nigeria

Epithelioid hemangioendothelioma (EHE), is a rare vascular tumor, described for the first time in 1975 by Dail and Liebow as an aggressive bronchoalveolar-cell carcinoma. The aetiology is still a dilemma to this day. Studies about suggestive hypothesis are ongoing. Most of the times, it affects lung, liver, and bones, but can arise from any part of the body. It has a very low prevalence of one in one million. Because of its heterogeneous presentation and rarity - represents <1% of all the vascular tumours, it is often misdiagnosed and not suitably treated, leading to a poor prognosis in some cases. Over 50%–76% of the patients are asymptomatic in the early stage of the disease. A small number of them complain of respiratory symptoms. Bone metastases might cause pathological fractures or cord compression if they arise in vertebrae. Imaging is necessary to determine extend of spread, the involvement of surrounding tissues, and potentially the cleavage plan. It is important to recognize the expression of vascular markers (Fli-1 and CD31 are endothelial-specific markers), and the microscopic evidence of vascular differentiation to make a correct diagnosis, as many pulmonary diseases show multiple nodular lesions. Because of its rarity, there is no standard treatment for EHE.


How to cite this article:
Nyaku FT, Dabkana TM, Nggada HA, Njem JM, Bwala ST, Gana YM. Epithelioid haemengioendothelioma: A report of two cases.Ann Trop Pathol 2019;10:77-80


How to cite this URL:
Nyaku FT, Dabkana TM, Nggada HA, Njem JM, Bwala ST, Gana YM. Epithelioid haemengioendothelioma: A report of two cases. Ann Trop Pathol [serial online] 2019 [cited 2024 Mar 29 ];10:77-80
Available from: https://www.atpjournal.org/article.asp?issn=2251-0060;year=2019;volume=10;issue=1;spage=77;epage=80;aulast=Nyaku;type=0