Annals of Tropical Pathology

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 8  |  Issue : 1  |  Page : 42--46

A point prevalence survey of antimicrobial prescribing in four Nigerian Tertiary Hospitals


OO Oduyebo1, AT Olayinka2, KC Iregbu3, A Versporten4, H Goossens4, PI Nwajiobi-Princewill3, O Jimoh2, TO Ige2, AI Aigbe3, OI Ola-Bello1, AO Aboderin5, FT Ogunsola1 
1 Department of Medical Microbiology, University of Lagos/Lagos University Teaching Hospital, Lagos, Nigeria
2 Department of Medical Microbiology, Ahmadu Bello University/Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
3 Department of Medical Microbiology, College of Health Sciences, University of Abuja/National Hospital, Abuja, Nigeria
4 Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium
5 Department of Medical, Microbiology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria

Correspondence Address:
O O Oduyebo
Department of Medical Microbiology, Lagos University Teaching Hospital, Lagos
Nigeria

Introduction: Antimicrobial resistance has become a global challenge in health care. Its emergence in previously sensitive bacteria is usually associated with poor antibiotic-prescribing patterns. Methodology: A point prevalence survey was carried out in four tertiary hospitals in Nigeria in 2015 to determine the rate and characteristics of antibiotic prescription. Results: Of 828 patients eligible for the study, 69.7% received antibiotics, with highest rates in the adult Intensive Care Unit. There were therapeutic indications in 51.2% of the prescriptions, of which 89.5% were for community-acquired infections. Third-generation cephalosporins were the most prescribed antibiotics. On the evaluation of surgical prophylaxis, only 4.1% were compliant with institutional guidelines and 39.2% gave a reason for prescribing in patient case notes. Less than 1% of the prescriptions were based on the use of biomarkers. Conclusion: The prevalence of antibiotic prescription in Nigerian hospitals is high with only about 50% of prescriptions based on clear therapeutic indications. We provide evidence that the country needs to institute a cohesive antimicrobial stewardship intervention program.


How to cite this article:
Oduyebo O O, Olayinka A T, Iregbu K C, Versporten A, Goossens H, Nwajiobi-Princewill P I, Jimoh O, Ige T O, Aigbe A I, Ola-Bello O I, Aboderin A O, Ogunsola F T. A point prevalence survey of antimicrobial prescribing in four Nigerian Tertiary Hospitals.Ann Trop Pathol 2017;8:42-46


How to cite this URL:
Oduyebo O O, Olayinka A T, Iregbu K C, Versporten A, Goossens H, Nwajiobi-Princewill P I, Jimoh O, Ige T O, Aigbe A I, Ola-Bello O I, Aboderin A O, Ogunsola F T. A point prevalence survey of antimicrobial prescribing in four Nigerian Tertiary Hospitals. Ann Trop Pathol [serial online] 2017 [cited 2024 Mar 28 ];8:42-46
Available from: https://www.atpjournal.org/article.asp?issn=2251-0060;year=2017;volume=8;issue=1;spage=42;epage=46;aulast=Oduyebo;type=0