• Users Online: 229
  • Print this page
  • Email this page
REVIEW ARTICLE
Year : 2022  |  Volume : 13  |  Issue : 1  |  Page : 1-3

Gastrointestinal stromal tumor – A systemic review literature


1 Demonstrator, Gauhati Medical College and Hospital, Gauhati, Assam, India
2 Senior Resident, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
3 Assistant Professor, Tezpur Medical College and Hospital, Tezpur, Assam, India

Correspondence Address:
Dr. Debajani Deka
C/o. P. C. Prafulla Chandra Deka, Bishnu Rabha Road, Tezpur, Assam
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/atp.atp_5_22

Rights and Permissions

Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors of the gastrointestinal tract and originate from the interstitial cells of Cajal. They arise most commonly from the stomach or small intestine, with a median age of 60 years. We did not find any relationship between GIST and ABO blood group and Rh factor. Mutations in KIT exon 11 are found to be more common in larger tumors, and the presence of this mutation has been shown to have an adverse prognostic influence. Deletions compared with point mutations in exon 11 have also been found to be a significant unfavorable factor in patients with gastric GISTs. The study group includes all cases of GIST and extra-GIST. Review literatures were taken from Internet Google search and some websites of high index journals. The data extruded mainly were sites of the gastrointestinal tract, histological types, different immunohistochemical markers, etc., Stomach is the most common site of GIST around 70%. Spindle cell is the most common histological variety; CD117 is frequently found immunohistochemical finding. From the abovementioned results, we can easily come to the diagnosis of specific type of GIST and its respective therapeutic measures.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1073    
    Printed70    
    Emailed0    
    PDF Downloaded100    
    Comments [Add]    

Recommend this journal